South Australia Police said a “serious” crash involving a car and a train occurred near the Augusta Highway in Winninowie, at about 12.30pm today.
9News understands the crash occurred between a freight train and a ute.
It is not yet known how many people were inside the car.
“Motorists are asked to take care travelling through the area as emergency services are in attendance and there may be delays,” South Australia Police said in a statement.
Major crash investigators are at the scene.